文章摘要
姬富才1,贾永平2*,吕吉元2,范春雨2,高宇平2,王睿2 ,王政2.动态脉压与冠状动脉病变狭窄程度的相关性研究[J].山西医科大学学报,2009,40(4):332~335
动态脉压与冠状动脉病变狭窄程度的相关性研究
Relationship between pulse pressures and severity of coronary artery stenosis
  
DOI:
中文关键词: 脉压  〓冠状动脉造影术  〓冠状动脉狭窄
英文关键词: pulse pressure  〓coronary angiography  〓coronary stenosis
基金项目:山西省教育厅高校科技研究开发基金资助项目(20041011)
作者单位
姬富才1,贾永平2*,吕吉元2,范春雨2,高宇平2,王睿2 ,王政2 1河南三门峡市中心医院心内科三门峡4720002山西医科大学第一临床医学院心内科*通讯作者Tel:0351-4639880 
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中文摘要:
      目的〓 探讨动态各脉压(PP)与冠脉病变狭窄程度的关系。 〓方法〓 对252例入选病例均行冠脉造影术,并据冠脉造影结果分为冠脉狭窄组(n=180)和非冠脉狭窄组(n=72);根据患者既往有无高血压病(EH)史分为EH组(n=164)和非EH组(n=88)。所有患者均于术后进行24 h动态血压监测(ABPM)。冠脉病变的狭窄程度用病变的血管支数及Gensini积分表示。 〓结果〓 EH组较非EH组冠心病(CHD)患病率明显增高(81.1% vs 53.4%,P=0.000)〖KG-*5〗;EH组双支、三支冠脉病变患病率均显著高于非EH组(28.7% vs 5.7%,P=0.000;29.3% vs 9.1%,P=0.000);冠脉狭窄组动态各收缩压(SBP)、PP均显著高于冠脉正常组(P<0.05),并且各动态PP随冠脉血管狭窄支数的增加而逐渐增加。多因素Logistic回归分析结果显示:24 h动态PP、白日动态PP、夜间动态PP、年龄均与CHD冠脉狭窄程度的关系密切。且夜间动态PP较其他因素与CHD冠脉狭窄程度关系更密切。 〓结论〓 动态各PP均是CHD冠脉狭窄发生发展的独立危险因素,且夜间动态PP的预测价值更佳。
英文摘要:
      Objective〓 To evaluate the relationship between ambulatory pulse pressure(PP)and the severity of coronary artery stenosis. 〓Methods〓 Coronary angiography was performed in 252 patients.According to the results of coronary angiography,all patients were allocated into coronary stenosis group(n=180)and coronary normal group(n=72).According to with or without essential hypertension(EH),all patients were divided into EH group(n=164)and non EH group(n=88).All patients performed 24 h ambulatory blood pressure monitor(ABPM)after coronary angiography.The severity of coronary artery stenosis was evaluated by the number of impaired arteries and Gensini score. 〓Results〓 Patients with EH showed a higher incidence of coronary heart disease(CHD)than those without EH(81.1% vs 53.4%, P=0.000).Patients with EH had a higher incidence of 2 and 3 coronary artery lesions than those without EH(28.7% vs 5.7%, P=0.000;29.3% vs 9.1%, P=0.000).Ambulatory systolic blood pressures(SBP),PP were significantly higher in patients with CHD than that in normal subjects(P<0.05).Logistic multivariate analysis showed that 24 h PP,daytime PP,nighttime PP and age were closely related to the severity of coronary artery lesions,especially nighttime PP. 〖WTBX〗〓Conclusion〖WTBZ〗〓 Different ambulatory PPs are all the independent risk factors of the severity of coronary artery stenosis,and the nighttime PP is the best predictor for severity of CHD. 〖JP〗
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