文章摘要
杜毓锋,刘学军,钱力.丙氨酰-谷氨酰胺治疗老年慢性阻塞性肺疾病急性加重期的临床观察[J].山西医科大学学报,2009,40(4):336~338
丙氨酰-谷氨酰胺治疗老年慢性阻塞性肺疾病急性加重期的临床观察
Effects of alanyl glutamine on acute exacerbation of chronic obstructive pulmonary disease in aged patients
  
DOI:
中文关键词: 慢性阻塞性肺疾病  〓丙氨酰谷氨酰胺  〓营养治疗
英文关键词: chronic obstructive pulmonary disease  〓alanyl glutamine  〓nutrition treatment
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作者单位
杜毓锋,刘学军,钱力 山西医科大学第一临床医学院老年病科太原030001 
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中文摘要:
      目的〓 探讨丙氨酰谷氨酰胺对慢性阻塞性肺疾病急性加重期患者(AECOPD)的治疗作用。 〓方法〓 选择60例AECOPD 患者,随机分为治疗组和对照组,各30例。对照组给予常规临床治疗,抗生素使用14 d。治疗组在对照组的基础上加用丙氨酰谷氨酰胺治疗,观察两组治疗前、治疗第10天及第14天的动脉血气,治疗前及治疗第14天的肝肾功能、血清白蛋白、总蛋白的变化,并评价治疗效果。 〓结果〓 治疗组动脉血气分析在第10天与对照组比较有统计学差异(P<0.05),治疗期间各营养指标明显高于对照组(P<0.05),肝肾功能无统计学差异(P>0.05),疗效评价治疗组与对照组相比有统计学差异(P<0.05)。 〓结论〓 联合应用丙氨酰谷氨酰胺对AECOPD患者有明显的治疗作用。
英文摘要:
      Objective〓 To evaluate the value of alanyl glutamine in the treatment of aged patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD). 〓Methods〓 Sixty aged patients with AECOPD were randomly divided into two groups:control group(n=30)and treatment group(n=30).The patients in control group were given the conventional treatment for 14 d,and patients in treatment group were given alanyl glutamine for 14 d based on conventional treatment.Before and after treatment,the arterial blood gas analysis was observed,liver and kidney functions,seralbumin and total serum protein were detected,and the clinical effects were evaluated. 〓Results〓 At day 10,the arterial blood gas analysis in treatment group was better than that in control group(P<0.05).During the whole treatment,all nutrition indices were higher than that in control group(P<0.05).The clinical effects in treatment group were better than that in control group(P<0.05),but the liver and kidney functions showed no significant difference between two groups(P>0.05). 〓Conclusion〓 Conventional treatment combined with alanyl glutamine could effectively treat AECPD in the aged patients.
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