文章摘要
索利斌,马宝成,王小军.盐酸雷莫司琼在预防术后恶心呕吐的临床研究[J].山西医科大学学报,2009,40(4):360~362
盐酸雷莫司琼在预防术后恶心呕吐的临床研究
Clinical study on intravenous injection of ramosetron for preventing postoperative nausea and vomiting
  
DOI:
中文关键词: 雷莫司琼  〓恶心  〓呕吐
英文关键词: ramosetron  〓nausea  〓vomiting
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作者单位
索利斌,马宝成,王小军 武警北京总队医院麻醉科北京100027 
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中文摘要:
      目的〓 探讨雷莫司琼预防手术后恶心呕吐的效果。 〓方法〓 75例择期在全身麻醉下行普外科手术的病人,按随机数字表随机分为3组:A组(雷莫司琼组,n=25),在麻醉诱导前静脉给予雷莫司琼0.3 mg;B组(昂丹司琼组,n=25),麻醉诱导前静脉给予昂丹司琼4 mg;C组(对照组,n=25),麻醉诱导前静脉注射0.9%生理盐水10 ml。观察每位病人手术后24 h的恶心、呕吐发生率。 〓结果〓 术后24 h雷莫司琼组和昂丹司琼组恶心呕吐发生率分别为8%和12%,显著低于对照组48%(P<0.05)。 〓结论〓 雷莫司琼能安全、有效的预防术后恶心呕吐的发生。
英文摘要:
      Objective〓 To study the efficacy of ramosetron for preventing postoperative nausea and vomiting. 〓Methods〓 A total of 75 patients performing selective surgery were divided into three groups:ramosetron group,ondensetron group and placebo group.Before anesthesia induction,the patients were given 0.3 mg ramosetron in ramosetron group,4 mg ondensetron in ondensetron group,while 10 ml normal saline in placebo group.The nausea and vomiting were observed and recorded after surgery for 24 h. 〓Results〓 The postoperative nausea and vomiting was significantly lower in ramosetron group(8%)and ondensetron group(12%)than that in placebo group(48%,P<0.05). 〓Conclusion〓 Ramosetron could effectively prevent postoperative nausea and vomiting.
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