文章摘要
马沁雅,梁景青*,康贵荣,张慧丰.DYS542在山西汉族人群中的多态性分布[J].山西医科大学学报,2009,40(1):56~57
DYS542在山西汉族人群中的多态性分布
Polymorphism of DYS542 in population of Han ethnicity in Shanxi province in China
  
DOI:
中文关键词: Y染色体  汉族  短串联重复序列  DYS542
英文关键词: Y chromosome  Han ethnicity  short tandem repeat  DYS542
基金项目:山西医科大学大学生创新基金资助项目(35)
作者单位
马沁雅,梁景青*,康贵荣,张慧丰 山西医科大学法医物证教研室太原030001*通讯作者E mail:liangjingqing@sina.com 
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中文摘要:
      目的〓 对DYS542基因座的基因多态性和法医学应用进行研究。 〓方法〓 随机抽取102例山西汉族男性无关个体静脉血,进行聚合酶链反应(PCR)扩增,银染显色。对其筛选的等位基因测序,构建等位基因分型标准物;按照国际法医遗传学会DNA委员会(ISFG)原则命名各等位基因。 〓结果〓 山西地区汉族男性DYS542基因座观察到14,15,16,17,18共5个等位基因,基因频率分别为0.106 8,0.407 8,0.349 5,0.126 2,0.009 7。该基因座核心重复单位是ATAG。 〓结论〓 Y染色体基因座DYS542具有较高的遗传多态性,在法医学及人类遗传学方面具有较高应用价值。
英文摘要:
      Objective〓 To investigate the gene polymorphism of locus DYS542 and its utilization. 〓Methods〓 The venous blood samples were randomly collected from 102 unrelated males in Shanxi province.Each allele of Y STR loci was sequenced and the allele ladders were constructed. Alleles of Y STR locus were nominated according to recommendations of the International Society of Forensic Genetics. 〓Results〓 Five alleles named 14,15,16,17,18 were observed with frequency of 0.106 8,0.407 8,0.349 5,0.126 2,0.009 7.The number of simple repeat nucleotide was four and the sequence was ATAG. 〓Conclusion〓 DYS542 has a high level of genetic polymorphism and can be used in forensic science and human genetics research.
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